The association between type of AF and the multinomial (more than two levels) outcomes (readmission and discharge disposition) were analyzed using multivariable generalized logistic regression using PROC SURVEYLOGISTIC (logit). The association between type of AF and the binary outcomes (mortality, stroke, composite outcome) were analyzed using multivariable logistic regression using PROC SURVEYLOGISTIC. Continuous variables are displayed as median (interquartile range). Categorical variables are displayed as percent weighted visits with 95% confidence of these estimates. Differences in baseline characteristics are evaluated using F-test results from a simple linear regression in PROC SURVEYREG for continuous variables (PROC SURVEYMEANS does not give P value of comparison groups, simple linear regression is an established workaround for this) and Rao Scott Chi-Square results from PROC SURVEYFREQ for categorical variables. PROC SURVEYFREEQ, PROC SURVEYMEANS, and PROC SURVEYREG were used to determined baseline characteristics. All analyses are performed on the weighted number of events in the cohort using complex survey procedures and domain analysis to ensure proper adjustment of standard errors. Statistical analysis was appropriately weighted using the weights supplied by the NRD to produce nationally representative estimates. Baseline characteristics were determined using SAS procedures designed to account for the complex sampling design of the NRD survey.
#Paroxysmal atrial fibrillation icd 10 software
Statistical Analysis System (SAS) software 9.4 (TS1M5, SAS Institute Inc., Cary, North Carolina) was used for statistical analysis. Our goal is to explore this impact based on 2016 Nationwide Readmission Database (NRD) for patients undergoing transcatheter MV repair. Whether any difference exists in the impact of paroxysmal versus non-paroxysmal AF on post-TMVR outcomes remains a subject of interest. Previous studies have shown that non-paroxysmal AF is associated with higher rate of stroke and mortality when compared to paroxysmal AF ( 8). Patients with degenerative MR and AF had higher risks of stroke, bleeding, death and HF hospitalizations, after TMVR. Almost half of the patients with degenerative MR have AF at 10 years ( 7). It has been categorized as paroxysmal (returns to sinus rhythm within 7 days), non-paroxysmal (returns to sinus rhythm after 7 days), or permanent (does not return to sinus rhythm) ( 6).
The MitraClip ® device system is now approved for repair of both degenerative and functional MR in US and has been proven to be effective in reducing MR, symptoms of heart failure, and left ventricular remodeling ( 3, 4).Ītrial fibrillation (AF) significantly increases the risk of cardioembolic events and heart failure ( 5). Transcatheter mitral valve repair (TMVR) has emerged as a promising treatment option for symptomatic patients with chronic severe primary mitral regurgitation for patients at higher surgical risk ( 1, 2).
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